DUR3/YHL016C Summary Help

Standard Name DUR3 1
Systematic Name YHL016C
Feature Type ORF, Verified
Description Plasma membrane transporter for both urea and polyamines; expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway (2, 3, 4, 5)
Name Description Degradation of URea 3
Chromosomal Location
ChrVIII:74244 to 72037 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -13 cM
Gene Ontology Annotations All DUR3 GO evidence and references
  View Computational GO annotations for DUR3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
25 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • PCA: 13
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 10
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 735
Molecular Weight (Da) 80,616
Isoelectric Point (pI) 5.44
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:74244 to 72037 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -13 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2208 74244..72037 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000001008
References cited on this page View Complete Literature Guide for DUR3
1) Cooper, T. and Mojumdar, M.  (1985) Personal Communication, Mortimer Map Edition 9
2) van Vuuren HJ, et al.  (1991) Upstream induction sequence, the cis-acting element required for response to the allantoin pathway inducer and enhancement of operation of the nitrogen-regulated upstream activation sequence in Saccharomyces cerevisiae. J Bacteriol 173(22):7186-95
3) ElBerry HM, et al.  (1993) Regulation of the urea active transporter gene (DUR3) in Saccharomyces cerevisiae. J Bacteriol 175(15):4688-98
4) Klebl F, et al.  (2003) A defect in the yeast plasma membrane urea transporter Dur3p is complemented by CpNIP1, a Nod26-like protein from zucchini (Cucurbita pepo L.), and by Arabidopsis thaliana delta-TIP or gamma-TIP. FEBS Lett 547(1-3):69-74
5) Uemura T, et al.  (2007) Polyamine Uptake by DUR3 and SAM3 in Saccharomyces cerevisiae. J Biol Chem 282(10):7733-41