Standard Name	BCK2
Systematic Name	YER167W
Alias	CTR7
Feature Type	ORF, Verified
Description	Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations (1)
Name Description	Bypass of C Kinase 1

Chromosomal Location	ChrV:518216 to 520771 | ORF Map | GBrowse

Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	G1/S transition of mitotic cell cycle (IGI) positive regulation of gene expression (IMP) regulation of cell cycle (IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Classical genetics
null	cell size: increased critical cell size at START (G1 cell-size checkpoint): increased pheromone sensitivity: increased resistance to Calcofluor White: decreased resistance to Congo Red: decreased
overexpression	cell size: decreased pheromone sensitivity: decreased resistance to Calcofluor White: increased
Large-scale survey
null	auxotrophy cell size: increased competitive fitness: decreased resistance to sodium arsenite: decreased resistance to bleomycin: decreased resistance to fluconazole: increased resistance to caffeine: increased resistance to cycloheximide: increased resistance to tunicamycin: decreased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to methyl methanesulfonate: increased resistance to St. John's Wort extract: decreased sporulation efficiency: increased stress resistance: decreased viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	116 total interaction(s) for 86 unique genes/features.
Physical Interactions	Affinity Capture-MS: 12 Affinity Capture-RNA: 1 Affinity Capture-Western: 4 Biochemical Activity: 1 Two-hybrid: 3
Genetic Interactions	Dosage Rescue: 16 Negative Genetic: 34 Phenotypic Enhancement: 14 Phenotypic Suppression: 2 Positive Genetic: 1 Synthetic Growth Defect: 6 Synthetic Lethality: 10 Synthetic Rescue: 12
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:518216 to 520771 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2556 518216..520771 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000969