Standard Name	PEA2 1
Systematic Name	YER149C
Alias	DFG9 , PPF2
Feature Type	ORF, Verified
Description	Coiled-coil polarisome protein required for polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; forms polarisome complex with Bni1p, Bud6p, and Spa2p; localizes to sites of polarized growth (1, 2, 3)
Name Description	PEAnut shmoo mutant 1

Chromosomal Location	ChrV:467470 to 466208 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

Molecular Function
Manually curated	cytoskeletal regulatory protein binding (TAS)
Biological Process
Manually curated	actin filament organization (TAS) bipolar cellular bud site selection (TAS) establishment of cell polarity (TAS) filamentous growth (IMP) pseudohyphal growth (IMP) regulation of initiation of mating projection growth (IMP) regulation of termination of mating projection growth (IMP) Rho protein signal transduction (TAS)
Cellular Component
Manually curated	actin cap (TAS) polarisome (IDA)
High-throughput	mating projection tip (IDA)

Classical genetics
null	SLT2-LacZ accumulation: decreased actin cytoskeleton morphology: abnormal cell fusion: decreased calcium(2+) accumulation: decreased mating efficiency: decreased Fig1p-Myc accumulation: increased Fus2p-GFP distribution: abnormal shmoo formation: abnormal
unspecified	pseudohyphal growth: decreased
Large-scale survey
null	auxotrophy bud morphology: abnormal chitin deposition: normal competitive fitness: decreased filamentous growth: decreased invasive growth: absent resistance to Calcofluor White: normal resistance to sorbate: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	94 total interaction(s) for 74 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-Western: 2 Reconstituted Complex: 2 Two-hybrid: 19
Genetic Interactions	Negative Genetic: 36 Phenotypic Enhancement: 2 Phenotypic Suppression: 3 Positive Genetic: 1 Synthetic Growth Defect: 9 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 15 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:467470 to 466208 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1263 467470..466208 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000951