MAG1/YER142C Summary

MAG1 BASIC INFORMATION

Standard Name	MAG1
Systematic Name	YER142C
Alias	MMS5 1
Feature Type	ORF, Verified
Description	3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired (2)
Name Description	3-MethylAdenine DNA Glycosylase 2

GO Annotations	All MAG1 GO evidence and references
	View Computational GO annotations for MAG1
Molecular Function
Manually curated	alkylbase DNA N-glycosylase activity (IDA)
Biological Process
Manually curated	DNA dealkylation (IEP, IGI, ISS)
Cellular Component
Manually curated	nucleus (IC)

Mutant Phenotype	All MAG1 Phenotype details and references
Classical genetics
null	resistance to methyl methanesulfonate: decreased
reduction of function	UV resistance: normal X ray resistance: normal resistance to methyl methanesulfonate: decreased
Large-scale survey
null	resistance to methyl methanesulfonate: decreased viable
overexpression	vegetative growth: decreased

Interactions	MAG1 All interactions details and references
	43 total interaction(s) for 34 unique genes/features.
Physical Interactions	Affinity Capture-MS: 16 Biochemical Activity: 1
Genetic Interactions	Phenotypic Enhancement: 19 Phenotypic Suppression: 3 Synthetic Rescue: 4

Sequence Information

ChrV:456031 to 455141 | |

Note: this feature is encoded on the Crick strand.

Genetic position: 110 cM

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..891	456031..455141	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000944

MAG1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MAG1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MAG1]

1)	Prakash L and Prakash S (1977) Isolation and characterization of MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 86(1):33-55
2)	Chen J, et al. (1989) Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli. Proc Natl Acad Sci U S A 86(20):7961-5

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