GDI1/YER136W Summary Help

GDI1 BASIC INFORMATION

Standard Name GDI1
Systematic Name YER136W
Alias SEC19 1
Feature Type ORF, Verified
Description GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins (2, 3)
Name Description GDP Dissociation Inhibitor
GO Annotations All GDI1 GO evidence and references
    View Computational GO annotations for GDI1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All GDI1 Phenotype details and references
Classical genetics
conditional
Large-scale survey
null
Interactions GDI1 All interactions details and references
76 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 28
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 7
  • Co-crystal Structure: 4
  • PCA: 9
  • Reconstituted Complex: 1
  • Two-hybrid: 12
Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Phenotypic Suppression: 1
  • Synthetic Lethality: 11
Sequence Information
ChrV:439612 to 440967 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1356 439612..440967 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000938

GDI1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for GDI1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GDI1]

1) Novick P, et al.  (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
2) Garrett MD, et al.  (1994) GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway. EMBO J 13(7):1718-28
3) Collins RN, et al.  (1997) Interactions of nucleotide release factor Dss4p with Sec4p in the post-Golgi secretory pathway of yeast. J Biol Chem 272(29):18281-9