PMD1/YER132C Summary Help

Standard Name PMD1 1
Systematic Name YER132C
Feature Type ORF, Verified
Description Protein with an N-terminal kelch-like domain; putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions; PMD1 has a paralog, MDS3, that arose from the whole genome duplication (1, 2, 3)
Name Description Paralog of MDS3 1
Chromosomal Location
ChrV:430449 to 425188 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PMD1 GO evidence and references
  View Computational GO annotations for PMD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Large-scale survey
null
overexpression
Resources
30 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 17
  • Affinity Capture-RNA: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 5
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,753
Molecular Weight (Da) 195,381
Isoelectric Point (pI) 7.8
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:430449 to 425188 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..5262 430449..425188 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000934
References cited on this page View Complete Literature Guide for PMD1
1) Benni ML and Neigeborn L  (1997) Identification of a new class of negative regulators affecting sporulation-specific gene expression in yeast. Genetics 147(3):1351-66
2) Davis DA, et al.  (2002) Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis. Genetics 162(4):1573-81
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61