YER130C Summary Help

Reserved Name COM2 1

This name is reserved with SGD according to the Gene Naming Guidelines agreed upon by the yeast community.
For more information about this reservation, please see the Locus History.
Systematic Name YER130C
Feature Type ORF, Uncharacterized
Description Protein of unknown function; transcription is regulated by Haa1p, Sok2p and Zap1p transcriptional activators; computational analysis suggests a role as a transcription factor; C. albicans homolog (MNL1) plays a role in adaptation to stress (2, 3, 4, 5, 6, 7)
Name Description Cousin of Msn2 1
Chromosomal Location
ChrV:422446 to 421115 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YER130C GO evidence and references
  View Computational GO annotations for YER130C
Molecular Function
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Regulatory Role
Binding motifs
Resources
Mutant phenotypes All YER130C Phenotype evidence and references
Large-scale survey
null
Resources
interactions All YER130C Interaction evidence and references
19 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Two-hybrid: 2
Genetic Interactions
  • Negative Genetic: 9
  • Positive Genetic: 5
  • Synthetic Lethality: 2
Resources
Expression Summary
histogram
Resources
Protein Information All YER130C Protein evidence and references
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:422446 to 421115 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1332 422446..421115 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000932
References cited on this page View Complete Literature Guide for YER130C
1) Petryshyn A, et al.  (2008) personal communication
2) Vachova L, et al.  (2004) Sok2p transcription factor is involved in adaptive program relevant for long term survival of Saccharomyces cerevisiae colonies. J Biol Chem 279(36):37973-81
3) Fernandes AR, et al.  (2005) Saccharomyces cerevisiae adaptation to weak acids involves the transcription factor Haa1p and Haa1p-regulated genes. Biochem Biophys Res Commun 337(1):95-103
4) De Nicola R, et al.  (2007) Physiological and Transcriptional Responses of Saccharomyces cerevisiae to Zinc Limitation in Chemostat Cultures. Appl Environ Microbiol 73(23):7680-92
5) Ramsdale M, et al.  (2008) MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans. Mol Biol Cell 19(10):4393-403
6) Mira NP, et al.  (2010) Genomic Expression Program Involving the Haa1p-Regulon in Saccharomyces cerevisiae Response to Acetic Acid. OMICS 14(5):587-601
7) Yang Y, et al.  (2010) Identifying cooperative transcription factors by combining ChIP-chip data and knockout data. Cell Res 20(11):1276-8
8) Zhu C, et al.  (2009) High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res 19(4):556-66
9) Badis G, et al.  (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32(6):878-87