BOI2/YER114C Summary

BOI2 BASIC INFORMATION

Standard Name	BOI2
Systematic Name	YER114C
Alias	BEB1
Feature Type	ORF, Verified
Description	Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain (1)
Name Description	Bem1 (One) Interacting protein 1, 2

GO Annotations	All BOI2 GO evidence and references
	View Computational GO annotations for BOI2
Molecular Function
Manually curated	phospholipid binding (ISS)
Biological Process
Manually curated	budding cell apical bud growth (IGI) cytokinesis, completion of separation (IGI) establishment of cell polarity (TAS) Rho protein signal transduction (TAS)
Cellular Component
Manually curated	cellular bud (IDA) cellular bud neck (IDA) site of polarized growth (IDA)

Mutant Phenotype	All BOI2 Phenotype details and references
Large-scale survey
null	filamentous growth: decreased invasive growth: absent replicative lifespan: increased resistance to ethanol: decreased respiratory growth: absent viable

Interactions	BOI2 All interactions details and references
	63 total interaction(s) for 45 unique genes/features.
Physical Interactions	Affinity Capture-MS: 6 Affinity Capture-Western: 1 Reconstituted Complex: 1 Two-hybrid: 31
Genetic Interactions	Dosage Rescue: 4 Phenotypic Enhancement: 10 Synthetic Growth Defect: 2 Synthetic Lethality: 8

Sequence Information

ChrV:393708 to 390586 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3123	393708..390586	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000916

BOI2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for BOI2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BOI2]

1)	Hallett MA, et al. (2002) Probing the importance and potential roles of the binding of the PH-domain protein Boi1 to acidic phospholipids. BMC Cell Biol 3():16
2)	Matsui Y, et al. (1996) Yeast src homology region 3 domain-binding proteins involved in bud formation. J Cell Biol 133(4):865-78

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