Standard Name	MAM1 1
Systematic Name	YER106W
Feature Type	ORF, Verified
Description	Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle (1)
Name Description	Monopolar microtubule Attachment during Meiosis I 1

Chromosomal Location	ChrV:372326 to 373234 | ORF Map | GBrowse

	View Computational GO annotations for MAM1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	meiotic chromosome segregation (IMP) meiotic sister chromatid cohesion involved in meiosis I (IGI, IMP)
Cellular Component
Manually curated	condensed nuclear chromosome kinetochore (IDA) monopolin complex (IDA)

Classical genetics
null	chromosome segregation: abnormal Spr1-GFP distribution: abnormal
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: increased haploinsufficient meiosis: abnormal resistance to cycloheximide: decreased resistance to amitrole: decreased spore germination: decreased sporulation: decreased vegetative growth: abnormal viable
overexpression	inviable resistance to LY-83583: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	32 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-Western: 2 Co-crystal Structure: 1 Co-localization: 1 Reconstituted Complex: 3 Two-hybrid: 9
Genetic Interactions	Negative Genetic: 2 Phenotypic Enhancement: 2 Phenotypic Suppression: 4 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:372326 to 373234 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..909 372326..373234 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000908