SHC1/YER096W Summary Help

Standard Name SHC1 1
Systematic Name YER096W
Feature Type ORF, Verified
Description Sporulation-specific activator of Chs3p (chitin synthase III); required for the synthesis of the chitosan layer of ascospores; transcriptionally induced at alkaline pH; SHC1 has a paralog, SKT5, that arose from the whole genome duplication (2, 3, 4)
Name Description Sporulation-specific Homolog of CSD4
Chromosomal Location
ChrV:351698 to 353236 | ORF Map | GBrowse
Gbrowse
Genetic position: 79.23 cM
Gene Ontology Annotations All SHC1 GO evidence and references
  View Computational GO annotations for SHC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Large-scale survey
null
overexpression
Resources
21 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1
  • Co-purification: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 10
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 512
Molecular Weight (Da) 56,578
Isoelectric Point (pI) 5.69
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:351698 to 353236 | ORF Map | GBrowse
SGD ORF map
Genetic position: 79.23 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1539 351698..353236 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000898
References cited on this page View Complete Literature Guide for SHC1
1) Bulawa, C.  (1993) Personal Communication, Mortimer Map Edition 12
2) Hong SK, et al.  (1999) SHC1, a high pH inducible gene required for growth at alkaline pH in Saccharomyces cerevisiae. Biochem Biophys Res Commun 255(1):116-22
3) Sanz M, et al.  (2002) Control of chitin synthesis through Shc1p, a functional homologue of Chs4p specifically induced during sporulation. Mol Microbiol 43(5):1183-95
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61