CEM1/YER061C Summary Help

Standard Name CEM1 1
Systematic Name YER061C
Feature Type ORF, Verified
Description Mitochondrial beta-keto-acyl synthase; possible role in fatty acid synthesis; required for mitochondrial respiration (1, 2)
Name Description Condensing Enzyme with Mitochondrial function 1
Chromosomal Location
ChrV:279626 to 278298 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CEM1 GO evidence and references
  View Computational GO annotations for CEM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 6 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
215 total interaction(s) for 163 unique genes/features.
Physical Interactions
  • Biochemical Activity: 1
  • PCA: 1

Genetic Interactions
  • Dosage Growth Defect: 2
  • Negative Genetic: 186
  • Positive Genetic: 18
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 442
Molecular Weight (Da) 47,555
Isoelectric Point (pI) 8.26
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:279626 to 278298 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1329 279626..278298 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000863
References cited on this page View Complete Literature Guide for CEM1
1) Harington A, et al.  (1993) Identification of a new nuclear gene (CEM1) encoding a protein homologous to a beta-keto-acyl synthase which is essential for mitochondrial respiration in Saccharomyces cerevisiae. Mol Microbiol 9(3):545-55
2) Harington A, et al.  (1994) Subcellular relocalization of a long-chain fatty acid CoA ligase by a suppressor mutation alleviates a respiration deficiency in Saccharomyces cerevisiae. EMBO J 13(23):5531-8