TIR1/YER011W Summary Help

TIR1 BASIC INFORMATION

Standard Name TIR1
Systematic Name YER011W
Alias SRP1
Feature Type ORF, Verified
Description Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking (1, 2, 3, 4)
Name Description TIp1-Related 2
GO Annotations All TIR1 GO evidence and references
    View Computational GO annotations for TIR1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All TIR1 Phenotype details and references
Large-scale survey
null
Interactions TIR1 All interactions details and references
5 total interaction(s) for 5 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-Western: 1
Genetic Interactions
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 2
Sequence Information
ChrV:175247 to 176011 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..765 175247..176011 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000813

TIR1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for TIR1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
SRP1Nomenclature conflictSRP1 has been used to refer to both SRP1/YNL189W, which encodes a protein involved in nucleocytoplasmic transport, and TIR1/YER011W, a serine-rich protein of the cell wall.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TIR1]

1) Kitagaki H, et al.  (1997) Identification and analysis of a static culture-specific cell wall protein, Tir1p/Srp1p in Saccharomyces cerevisiae. Eur J Biochem 249(1):343-9
2) Kowalski LR, et al.  (1995) Cold-shock induction of a family of TIP1-related proteins associated with the membrane in Saccharomyces cerevisiae. Mol Microbiol 15(2):341-53
3) Marguet D, et al.  (1988) Yeast gene SRP1 (serine-rich protein). Intragenic repeat structure and identification of a family of SRP1-related DNA sequences. J Mol Biol 202(3):455-70
4) Cohen BD, et al.  (2001) Induction and repression of DAN1 and the family of anaerobic mannoprotein genes in Saccharomyces cerevisiae occurs through a complex array of regulatory sites. Nucleic Acids Res 29(3):799-808