NTF2/YER009W Summary Help

Standard Name NTF2
Systematic Name YER009W
Feature Type ORF, Verified
Description Nuclear envelope protein; interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport (1, 2)
Name Description Nuclear Transport Factor
Chromosomal Location
ChrV:172115 to 172492 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NTF2 GO evidence and references
  View Computational GO annotations for NTF2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
conditional
dominant negative
Large-scale survey
conditional
null
overexpression
Resources
25 total interaction(s) for 20 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 5
  • Affinity Capture-Western: 2
  • Biochemical Activity: 1
  • PCA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Lethality: 4
  • Dosage Rescue: 4
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 125
Molecular Weight (Da) 14,453
Isoelectric Point (pI) 4.35
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:172115 to 172492 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..378 172115..172492 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000811
References cited on this page View Complete Literature Guide for NTF2
1) Corbett AH and Silver PA  (1996) The NTF2 gene encodes an essential, highly conserved protein that functions in nuclear transport in vivo. J Biol Chem 271(31):18477-84
2) Quimby BB, et al.  (2001) Functional analysis of the hydrophobic patch on nuclear transport factor 2 involved in interactions with the nuclear pore in vivo. J Biol Chem 276(42):38820-9