MNN1/YER001W Summary Help

Standard Name MNN1 1
Systematic Name YER001W
Feature Type ORF, Verified
Description Alpha-1,3-mannosyltransferase; integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family (2, 3, 4)
Name Description MaNNosyltransferase
Chromosomal Location
ChrV:153520 to 155808 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MNN1 GO evidence and references
  View Computational GO annotations for MNN1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 141 genes
Resources
Classical genetics
unspecified
Large-scale survey
null
Resources
35 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Co-localization: 1
  • PCA: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 14
  • Phenotypic Enhancement: 4
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 762
Molecular Weight (Da) 88,529
Isoelectric Point (pI) 7.23
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:153520 to 155808 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2289 153520..155808 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000803
References cited on this page View Complete Literature Guide for MNN1
1) Raschke WC, et al.  (1973) Genetic control of yeast mannan structure. Isolation and characterization of mannan mutants. J Biol Chem 248(13):4660-6
2) Graham TR, et al.  (1994) Clathrin-dependent localization of alpha 1,3 mannosyltransferase to the Golgi complex of Saccharomyces cerevisiae. J Cell Biol 127(3):667-78
3) Lussier M, et al.  (1999) The KTR and MNN1 mannosyltransferase families of Saccharomyces cerevisiae. Biochim Biophys Acta 1426(2):323-34
4) Yip CL, et al.  (1994) Cloning and analysis of the Saccharomyces cerevisiae MNN9 and MNN1 genes required for complex glycosylation of secreted proteins. Proc Natl Acad Sci U S A 91(7):2723-7