Standard Name	SIT1 1 (see Nomenclature conflict Note)
Systematic Name	YEL065W
Alias	ARN3 2
Feature Type	ORF, Verified
Description	Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; transcription is induced during iron deprivation and diauxic shift; potentially phosphorylated by Cdc28p (3, 4, 5)
Name Description	Siderophore Iron Transport 1

Chromosomal Location	ChrV:27657 to 29543 | ORF Map | GBrowse

	View Computational GO annotations for SIT1
Molecular Function
Manually curated	siderophore uptake transmembrane transporter activity (IMP, ISS)
Biological Process
Manually curated	cellular iron ion homeostasis (IDA, IMP) siderophore transport (IMP) transmembrane transport (IMP)
Cellular Component
Manually curated	cytoplasmic membrane-bounded vesicle (IDA) endosome (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	viable
Large-scale survey
null	competitive fitness: normal metal resistance: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	31 total interaction(s) for 27 unique genes/features.
Physical Interactions	Affinity Capture-Western: 3 Biochemical Activity: 2 Protein-RNA: 1 Reconstituted Complex: 1 Two-hybrid: 2
Genetic Interactions	Negative Genetic: 12 Phenotypic Enhancement: 2 Positive Genetic: 1 Synthetic Growth Defect: 4 Synthetic Lethality: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:27657 to 29543 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1887 27657..29543 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000000791