Standard Name	IES6 1
Systematic Name	YEL044W
Feature Type	ORF, Verified
Description	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes (1, 2, 3)
Name Description	Ino Eighty Subunit 1

Chromosomal Location	ChrV:69757 to 70257 | ORF Map | GBrowse

	View Computational GO annotations for IES6
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
High-throughput	nucleus (IDA)

Classical genetics
null	auxotrophy Ptr2p-GFP accumulation: increased telomere length: increased
Large-scale survey
null	anaerobic growth: decreased bud morphology: abnormal cell size: increased proton accumulation: decreased glycogen accumulation: increased chitin deposition: increased competitive fitness: decreased haploproficient heat sensitivity: increased inviable nutrient utilization: increased resistance to cycloheximide: decreased resistance to Calcofluor White: decreased resistance to hydroxyurea: decreased resistance to 5-fluorouracil: decreased resistance to CTBT: decreased resistance to camptothecin: decreased resistance to tunicamycin: decreased resistance to wortmannin: decreased resistance to hydrogen chloride: decreased resistance to dimethyl sulfoxide: decreased resistance to cadmium dichloride: decreased resistance to L-1,4-dithiothreitol: decreased resistance to caffeine: decreased resistance to hygromycin B: decreased resistance to doxorubicin: decreased resistance to sorbate: decreased sporulation: absent toxin resistance: decreased transposable element transposition: decreased utilization of carbon source: decreased utilization of iron source: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	35 total interaction(s) for 33 unique genes/features.
Physical Interactions	Affinity Capture-MS: 11 Affinity Capture-RNA: 4
Genetic Interactions	Dosage Lethality: 1 Synthetic Growth Defect: 9 Synthetic Lethality: 9 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:69757 to 70257 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..501 69757..70257 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000770