Standard Name	GDA1
Systematic Name	YEL042W
Feature Type	ORF, Verified
Description	Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate (1)
Name Description	Guanosine DiphosphatAse

Chromosomal Location	ChrV:73771 to 75327 | ORF Map | GBrowse

	View Computational GO annotations for GDA1
Molecular Function
Manually curated	guanosine-diphosphatase activity (IDA) uridine-diphosphatase activity (IDA)
Biological Process
Manually curated	protein glycosylation (TAS)
Cellular Component
Manually curated	Golgi apparatus (TAS)

Classical genetics
null	toxin resistance: decreased
Large-scale survey
null	glycogen accumulation: increased competitive fitness: decreased dessication resistance: decreased resistance to ethanol: decreased resistance to neomycin: decreased resistance to paromomycin: decreased resistance to cycloheximide: decreased resistance to cycloheximide: increased resistance to fluconazole: increased resistance to mycophenolic acid: increased resistance to bleomycin: decreased resistance to dimethyl sulfoxide: decreased resistance to tunicamycin: decreased resistance to caffeine: decreased resistance to camptothecin: decreased sporulation efficiency: increased starvation resistance: decreased stress resistance: decreased toxin resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	163 total interaction(s) for 90 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Biochemical Activity: 1 PCA: 1 Two-hybrid: 5
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 107 Phenotypic Enhancement: 22 Phenotypic Suppression: 4 Positive Genetic: 14 Synthetic Growth Defect: 1 Synthetic Lethality: 2 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:73771 to 75327 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1557 73771..75327 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000768