EDC3/YEL015W Summary

EDC3 BASIC INFORMATION

Standard Name	EDC3 1
Systematic Name	YEL015W
Alias	DCP3 , LSM16
Feature Type	ORF, Verified
Description	Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically affecting the function of the decapping enzyme Dcp1p; localizes to cytoplasmic mRNA processing bodies (2)
Name Description	Enhancer of mRNA DeCapping 1, 2

GO Annotations	All EDC3 GO evidence and references
	View Computational GO annotations for EDC3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	cytoplasmic mRNA processing body assembly (IGI, IMP) deadenylation-independent decapping of nuclear-transcribed mRNA (IMP)
Cellular Component
Manually curated	cytoplasmic mRNA processing body (IDA)

Mutant Phenotype	All EDC3 Phenotype details and references
Classical genetics
null	viable
Large-scale survey
null	viable

Interactions	EDC3 All interactions details and references
	100 total interaction(s) for 54 unique genes/features.
Physical Interactions	Affinity Capture-MS: 27 Affinity Capture-Western: 1 Biochemical Activity: 3 PCA: 3 Protein-peptide: 1 Reconstituted Complex: 2 Two-hybrid: 33
Genetic Interactions	Phenotypic Enhancement: 13 Phenotypic Suppression: 2 Synthetic Growth Defect: 12 Synthetic Lethality: 2 Synthetic Rescue: 1

Sequence Information

ChrV:126629 to 128284 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1656	126629..128284	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000741

EDC3 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for EDC3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for EDC3]

1)	Samanta MP and Liang S (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83
2)	Kshirsagar M and Parker R (2004) Identification of Edc3p as an enhancer of mRNA decapping in Saccharomyces cerevisiae. Genetics 166(2):729-39

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