GIT1/YCR098C Summary

GIT1 BASIC INFORMATION

Standard Name	GIT1 1
Systematic Name	YCR098C
Feature Type	ORF, Verified
Description	Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability (1, 2, 3)
Name Description	GlycerophosphoInosiTol 1

GO Annotations	All GIT1 GO evidence and references
	View Computational GO annotations for GIT1
Molecular Function
Manually curated	glycerophosphodiester transmembrane transporter activity (IMP)
Biological Process
Manually curated	glycerophosphodiester transport (IMP) transmembrane transport (IMP)
Cellular Component
Manually curated	plasma membrane (IMP, ISS)

Mutant Phenotype	All GIT1 Phenotype details and references
Classical genetics
null	utilization of phosphorus source: decreased
Large-scale survey
null	competitive fitness: decreased viable

Interactions	GIT1 All interactions details and references
	15 total interaction(s) for 14 unique genes/features.
Physical Interactions	Two-hybrid: 5
Genetic Interactions	Dosage Rescue: 6 Synthetic Growth Defect: 3 Synthetic Rescue: 1

Sequence Information

ChrIII:298602 to 297046 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2006-01-12 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1557	298602..297046	2006-01-12	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000000695

GIT1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for GIT1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GIT1]

1)	Patton-Vogt JL and Henry SA (1998) GIT1, a gene encoding a novel transporter for glycerophosphoinositol in Saccharomyces cerevisiae. Genetics 149(4):1707-15
2)	Almaguer C, et al. (2003) Inositol and phosphate regulate GIT1 transcription and glycerophosphoinositol incorporation in Saccharomyces cerevisiae. Eukaryot Cell 2(4):729-36
3)	Fisher E, et al. (2005) Glycerophosphocholine-dependent growth requires Gde1p (YPL110c) and Git1p in Saccharomyces cerevisiae. J Biol Chem 280(43):36110-7

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