GIT1/YCR098C Summary Help

Standard Name GIT1 1
Systematic Name YCR098C
Feature Type ORF, Verified
Description Plasma membrane permease; mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability (1, 2, 3)
Name Description GlycerophosphoInosiTol 1
Chromosomal Location
ChrIII:298605 to 297049 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All GIT1 GO evidence and references
  View Computational GO annotations for GIT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
unspecified
Resources
16 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • PCA: 5

Genetic Interactions
  • Negative Genetic: 3
  • Phenotypic Suppression: 1
  • Positive Genetic: 3
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 518
Molecular Weight (Da) 57,321
Isoelectric Point (pI) 8.64
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:298605 to 297049 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1557 298605..297049 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000000695
References cited on this page View Complete Literature Guide for GIT1
1) Patton-Vogt JL and Henry SA  (1998) GIT1, a gene encoding a novel transporter for glycerophosphoinositol in Saccharomyces cerevisiae. Genetics 149(4):1707-15
2) Almaguer C, et al.  (2003) Inositol and phosphate regulate GIT1 transcription and glycerophosphoinositol incorporation in Saccharomyces cerevisiae. Eukaryot Cell 2(4):729-36
3) Fisher E, et al.  (2005) Glycerophosphocholine-dependent growth requires Gde1p (YPL110c) and Git1p in Saccharomyces cerevisiae. J Biol Chem 280(43):36110-7