Standard Name	FIG2 1
Systematic Name	YCR089W
Feature Type	ORF, Verified
Description	Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating; FIG2 has a paralog, AGA1, that arose from the whole genome duplication (1, 2, 3)
Name Description	Factor-Induced Gene 1

Chromosomal Location	ChrIII:267434 to 272263 | ORF Map | GBrowse

	View Computational GO annotations for FIG2
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	cell morphogenesis involved in conjugation with cellular fusion (IMP) cytogamy (IMP) filamentous growth of a population of unicellular organisms (IMP) invasive growth in response to glucose limitation (IMP)
Cellular Component
Manually curated	fungal-type cell wall (IDA) mating projection (IDA)

Classical genetics
null	cell fusion: decreased mating efficiency: decreased mating efficiency: increased mating projection morphology: abnormal nuclear fusion during mating: abnormal Stu2p-GFP distribution: abnormal Slt2p modification: increased spindle morphology: abnormal viability: decreased
overexpression	adhesion: increased filamentous growth: increased
Large-scale survey
null	auxotrophy competitive fitness: decreased resistance to neomycin: decreased resistance to cycloheximide: decreased resistance to benzo[a]pyrene: decreased resistance to pyocyanin: decreased sporulation efficiency: increased viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	35 total interaction(s) for 28 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 2 Affinity Capture-Western: 1 Protein-RNA: 1
Genetic Interactions	Negative Genetic: 11 Phenotypic Enhancement: 5 Phenotypic Suppression: 4 Positive Genetic: 1 Synthetic Growth Defect: 3 Synthetic Lethality: 5 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:267434 to 272263 | ORF Map | GBrowse
	This feature contains embedded feature(s): YCRX18C
Last Update	Coordinates: 2011-02-03 | Sequence: 2000-09-13
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..4830 267434..272263 2011-02-03 2000-09-13
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain EC1118 S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000685