Standard Name	BUD31 1
Systematic Name	YCR063W
Alias	CWC14 2
Feature Type	ORF, Verified
Description	Component of the SF3b subcomplex of the U2 snRNP; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; facilitates passage through G1/S Start, but is not required for G2/M transition or exit from mitosis (1, 3, 4, 5)
Name Description	BUD site selection 1

Chromosomal Location	ChrIII:228318 to 228791 | ORF Map | GBrowse

	View Computational GO annotations for BUD31
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	mRNA splicing, via spliceosome (IPI) RNA splicing (IPI)
High-throughput	cellular bud site selection (IMP)
Cellular Component
Manually curated	U2 snRNP (IDA)
High-throughput	nucleus (IDA)

Classical genetics
null	Unspliced ARP2 pre-mRNA accumulation: increased actin cytoskeleton morphology: abnormal bud morphology: abnormal cell cycle progression in G1 phase: delayed cell size: increased heat sensitivity: increased vegetative growth: decreased
Large-scale survey
null	budding pattern: abnormal cell cycle progression in G1 phase: increased duration cell shape: abnormal cell size: increased competitive fitness: decreased dessication resistance: decreased endocytosis: decreased fermentative growth: decreased rate haploinsufficient heat sensitivity: increased metal resistance: decreased resistance to cycloheximide: decreased resistance to benomyl: decreased resistance to oleate: decreased resistance to cisplatin: decreased resistance to glucose: decreased resistance to sodium arsenite: decreased resistance to 2,4-dichlorophenol: decreased resistance to ethanol: decreased resistance to amiodarone: decreased resistance to sorbate: decreased resistance to doxorubicin: decreased resistance to mycophenolic acid: decreased resistance to hygromycin B: decreased stress resistance: increased toxin resistance: decreased transposable element transposition: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	208 total interaction(s) for 190 unique genes/features.
Physical Interactions	Affinity Capture-MS: 41 Affinity Capture-RNA: 1 Co-purification: 1 Two-hybrid: 3
Genetic Interactions	Dosage Lethality: 1 Negative Genetic: 116 Positive Genetic: 38 Synthetic Growth Defect: 5 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:228318 to 228791 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..474 228318..228791 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000659