Standard Name	CWH43
Systematic Name	YCR017C
Feature Type	ORF, Verified
Description	Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion (1)
Name Description	Calcofluor White Hypersensitive 2

Chromosomal Location	ChrIII:147634 to 144773 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for CWH43
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	fungal-type cell wall organization (IGI) GPI anchor biosynthetic process (IMP)
Cellular Component
Manually curated	cellular bud neck (IDA) cellular bud tip (IDA) integral to plasma membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
unspecified	resistance to Calcofluor White: decreased
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased endocytosis: decreased haploinsufficient resistance to sodium arsenite: decreased resistance to L-canavanine: increased resistance to mefloquine: decreased sporulation efficiency: increased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	93 total interaction(s) for 58 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Biochemical Activity: 1
Genetic Interactions	Dosage Growth Defect: 1 Dosage Rescue: 5 Negative Genetic: 28 Phenotypic Enhancement: 40 Phenotypic Suppression: 4 Positive Genetic: 7 Synthetic Growth Defect: 3 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:147634 to 144773 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 2000-09-13
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2862 147634..144773 2011-02-03 2000-09-13
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000610