VAC17/YCL063W Summary Help

Standard Name VAC17 1, 2
Systematic Name YCL063W
Alias YCL062W
Feature Type ORF, Verified
Description Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p (1, 2, 3)
Name Description VACuole related 1
Chromosomal Location
ChrIII:17290 to 18561 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All VAC17 GO evidence and references
  View Computational GO annotations for VAC17
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 9 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
68 total interaction(s) for 46 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 8
  • Biochemical Activity: 1
  • PCA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 11

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Negative Genetic: 32
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 423
Molecular Weight (Da) 47,843
Isoelectric Point (pI) 8.6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:17290 to 18561 | ORF Map | GBrowse
This feature contains embedded feature(s): YCL062W
SGD ORF map
Last Update Coordinates: 2000-09-13 | Sequence: 2000-09-13
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1272 17290..18561 2000-09-13 2000-09-13
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000568
References cited on this page View Complete Literature Guide for VAC17
1) Tang F, et al.  (2003) Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole. Nature 422(6927):87-92
2) Ishikawa K, et al.  (2003) Identification of an organelle-specific myosin V receptor. J Cell Biol 160(6):887-97
3) Bartholomew CR and Hardy CF  (2009) p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae. Eukaryot Cell 8(4):560-72