Standard Name	FYV5
Systematic Name	YCL058C
Alias	MDF1 1
Feature Type	ORF, Verified
Description	Protein involved in regulation of the mating pathway; binds with Matalpha2p to promoters of haploid-specific genes; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis (1, 2, 3)
Name Description	Function required for Yeast Viability 3

Chromosomal Location	ChrIII:23981 to 23523 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for FYV5
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	cellular ion homeostasis (IMP) pheromone-dependent signal transduction involved in conjugation with cellular fusion (IMP)
Cellular Component
High-throughput	integral to membrane (ISM)

Resources	YeTFaSCo

Large-scale survey
null	budding index: decreased cell cycle progression in G1 phase: increased duration cell size: decreased competitive fitness: decreased fermentative growth: decreased rate hyperosmotic stress resistance: decreased ionic stress resistance: decreased resistance to paromomycin: decreased resistance to cycloheximide: decreased resistance to sirolimus: increased resistance to neomycin: decreased resistance to dimethyl sulfoxide: decreased resistance to L-1,4-dithiothreitol: decreased resistance to doxorubicin: decreased resistance to sorbate: decreased resistance to wortmannin: increased starvation resistance: decreased stress resistance: increased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:23981 to 23523 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	This feature contains embedded feature(s): ADF1
Last Update	Coordinates: 2000-09-13 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..459 23981..23523 2000-09-13 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000563