| Standard Name | SRO9 1 |
|---|---|
| Systematic Name | YCL037C |
| Feature Type | ORF, Verified |
| Description | Cytoplasmic RNA-binding protein; associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif; SRO9 has a paralog, SLF1, that arose from the whole genome duplication (1, 2, 3, 4) |
| Name Description | Suppressor of rho3 1 |
| Chromosomal Location | |
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| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All SRO9 GO evidence and references
| View Computational GO annotations for SRO9 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All SRO9 Phenotype evidence and references
interactions All SRO9 Interaction evidence and references
| 1032 total interaction(s) for 935 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All SRO9 Protein evidence and references
| Localization | |
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| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2003-09-22 | Sequence: 2003-09-22 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000000542 |
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References cited on this page View Complete Literature Guide for SRO9
| 1) | Kagami M, et al. (1997) SRO9, a multicopy suppressor of the bud growth defect in the Saccharomyces cerevisiae rho3-deficient cells, shows strong genetic interactions with tropomyosin genes, suggesting its role in organization of the actin cytoskeleton. Genetics 147(3):1003-16 |
| 2) | Sobel SG and Wolin SL (1999) Two yeast La motif-containing proteins are RNA-binding proteins that associate with polyribosomes. Mol Biol Cell 10(11):3849-62 |
| 3) | Hon T, et al. (2001) The Hsp70-Ydj1 molecular chaperone represses the activity of the heme activator protein Hap1 in the absence of heme. Mol Cell Biol 21(23):7923-32 |
| 4) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |




