BIK1/YCL029C Summary Help

BIK1 BASIC INFORMATION

Standard Name BIK1 1
Systematic Name YCL029C
Alias ARM5 , PAC14 2
Feature Type ORF, Verified
Description Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170 (3)
Name Description BIlateral Karyogamy defect 1
GO Annotations All BIK1 GO evidence and references
    View Computational GO annotations for BIK1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All BIK1 Phenotype details and references
Classical genetics
conditional
null
overexpression
reduction of function
Large-scale survey
null
overexpression
Interactions BIK1 All interactions details and references
138 total interaction(s) for 76 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-Western: 11
  • Biochemical Activity: 4
  • Co-localization: 1
  • Reconstituted Complex: 3
  • Two-hybrid: 13
Genetic Interactions
  • Phenotypic Enhancement: 20
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 11
  • Synthetic Lethality: 66
  • Synthetic Rescue: 1
Sequence Information
ChrIII:69921 to 68599 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -21 cM
Last Update Coordinates: 2000-09-13 | Sequence: 2000-09-13
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1323 69921..68599 2000-09-13 2000-09-13
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000534

BIK1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for BIK1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BIK1]

1) Trueheart J, et al.  (1987) Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol Cell Biol 7(7):2316-28
2) Geiser JR, et al.  (1997) Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol Biol Cell 8(6):1035-50
3) Berlin V, et al.  (1990) BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin. J Cell Biol 111(6 Pt 1):2573-86