AGP1/YCL025C Summary

AGP1 BASIC INFORMATION

Standard Name	AGP1
Systematic Name	YCL025C
Alias	YCC5
Feature Type	ORF, Verified
Description	Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) (1, 2)
Name Description	high-Affinity Glutamine Permease 1

GO Annotations	All AGP1 GO evidence and references
	View Computational GO annotations for AGP1
Molecular Function
Manually curated	amino acid transmembrane transporter activity (IDA) L-proline transmembrane transporter activity (IGI)
Biological Process
Manually curated	amino acid transport (IDA) transmembrane transport (IDA)
Cellular Component
Manually curated	plasma membrane (ISS)

Mutant Phenotype	All AGP1 Phenotype details and references
Classical genetics
null	glycogen accumulation: increased chronological lifespan: increased resistance to quinine: increased
Large-scale survey
null	viable

Interactions	AGP1 All interactions details and references
	65 total interaction(s) for 50 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Two-hybrid: 36
Genetic Interactions	Phenotypic Enhancement: 22 Phenotypic Suppression: 2 Synthetic Growth Defect: 3 Synthetic Lethality: 1

Sequence Information

ChrIII:77919 to 76018 | |

Note: this feature is encoded on the Crick strand.

This feature contains embedded feature(s): YCLX09W

Last Update

Coordinates: 2006-01-12 | Sequence: 2006-01-12

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1902	77919..76018	2006-01-12	2006-01-12

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000000530

AGP1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for AGP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for AGP1]

1)	Schreve JL, et al. (1998) The Saccharomyces cerevisiae YCC5 (YCL025c) gene encodes an amino acid permease, Agp1, which transports asparagine and glutamine. J Bacteriol 180(9):2556-9
2)	Forsberg H, et al. (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28

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