GBP2/YCL011C Summary Help

GBP2 BASIC INFORMATION

Standard Name GBP2 1
Systematic Name YCL011C
Alias RLF6 2
Feature Type ORF, Verified
Description Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro (1, 3)
Name Description G-strand Binding Protein 1
GO Annotations All GBP2 GO evidence and references
    View Computational GO annotations for GBP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All GBP2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions GBP2 All interactions details and references
140 total interaction(s) for 90 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 76
  • Affinity Capture-RNA: 6
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 40
  • Phenotypic Suppression: 11
  • Synthetic Lethality: 2
Sequence Information
ChrIII:103358 to 102075 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2006-01-12 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1284 103358..102075 2006-01-12 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000517

GBP2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for GBP2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GBP2]

1) Lin JJ and Zakian VA  (1994) Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitro. Nucleic Acids Res 22(23):4906-13
2) Konkel LM, et al.  (1995) A class of single-stranded telomeric DNA-binding proteins required for Rap1p localization in yeast nuclei. Proc Natl Acad Sci U S A 92(12):5558-62
3) Hurt E, et al.  (2004) Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex. Proc Natl Acad Sci U S A 101(7):1858-62