ILV6/YCL009C Summary Help

Standard Name ILV6 1
Systematic Name YCL009C
Feature Type ORF, Verified
Description Regulatory subunit of acetolactate synthase; acetolactate synthase catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria (1, 2)
Name Description IsoLeucine Valine 1
Chromosomal Location
ChrIII:105548 to 104619 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ILV6 GO evidence and references
  View Computational GO annotations for ILV6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 13 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
67 total interaction(s) for 52 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 15
  • Affinity Capture-RNA: 3
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 25
  • Phenotypic Suppression: 3
  • Positive Genetic: 19
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 309
Molecular Weight (Da) 33,986
Isoelectric Point (pI) 6.51
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:105548 to 104619 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2006-01-12 | Sequence: 1999-07-17
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..930 105548..104619 2006-01-12 1999-07-17
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000515
References cited on this page View Complete Literature Guide for ILV6
1) Cullin C, et al.  (1996) Functional analysis of YCL09C: evidence for a role as the regulatory subunit of acetolactate synthase. Yeast 12(15):1511-8
2) Pang SS and Duggleby RG  (1999) Expression, purification, characterization, and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase. Biochemistry 38(16):5222-31