Standard Name	ILV6 1
Systematic Name	YCL009C
Feature Type	ORF, Verified
Description	Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria (1, 2)
Name Description	IsoLeucine Valine 1

Chromosomal Location	ChrIII:105548 to 104619 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for ILV6
Molecular Function
Manually curated	acetolactate synthase activity (IDA) enzyme regulator activity (IDA)
Biological Process
Manually curated	branched-chain amino acid biosynthetic process (IDA, ISS)
Cellular Component
Manually curated	acetolactate synthase complex (IDA) mitochondrial nucleoid (IDA)
High-throughput	mitochondrion (IDA)

Pathways	acetoin biosynthesis isoleucine biosynthesis superpathway of acetoin and butanediol biosynthesis superpathway of leucine, isoleucine, and valine biosynthesis valine biosynthesis

Classical genetics
null	oxidative stress resistance: decreased viable
Large-scale survey
null	competitive fitness: increased haploproficient resistance to sulfometuron methyl: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	66 total interaction(s) for 53 unique genes/features.
Physical Interactions	Affinity Capture-MS: 14 Affinity Capture-RNA: 3 Reconstituted Complex: 1
Genetic Interactions	Negative Genetic: 25 Phenotypic Suppression: 3 Positive Genetic: 19 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:105548 to 104619 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2006-01-12 | Sequence: 1999-07-17
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..930 105548..104619 2006-01-12 1999-07-17
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000515