Standard Name	RER1 1
Systematic Name	YCL001W
Feature Type	ORF, Verified
Description	Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER (1, 2)
Name Description	Retention in the Endoplasmic Reticulum 1

Chromosomal Location	ChrIII:111916 to 112482 | ORF Map | GBrowse

	View Computational GO annotations for RER1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IPI) protein retention in ER lumen (IMP) retrograde vesicle-mediated transport, Golgi to ER (IDA, IMP)
Cellular Component
Manually curated	COPI-coated vesicle (IDA, IMP) ER to Golgi transport vesicle (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	Sec71p-GFP distribution: abnormal resistance to canavanine: decreased viable
reduction of function	Sec12p distribution: abnormal Sec12p modification: abnormal
Large-scale survey
null	rubidium(1+) accumulation: increased competitive fitness: decreased dessication resistance: decreased resistance to cycloheximide: increased resistance to hygromycin B: decreased resistance to ethanol: decreased resistance to bleomycin: decreased resistance to hydroxyurea: decreased resistance to methyl methanesulfonate: decreased resistance to fenpropimorph: increased starvation resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	211 total interaction(s) for 107 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 3 Affinity Capture-Western: 4 Co-fractionation: 1 Co-purification: 1 PCA: 3
Genetic Interactions	Negative Genetic: 112 Phenotypic Enhancement: 58 Phenotypic Suppression: 11 Positive Genetic: 9 Synthetic Growth Defect: 5 Synthetic Lethality: 1 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:111916 to 112482 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1999-07-17
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..567 111916..112482 2011-02-03 1999-07-17
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000507