APM3/YBR288C Summary Help

APM3 BASIC INFORMATION

Standard Name APM3
Systematic Name YBR288C
Alias YKS6 1
Feature Type ORF, Verified
Description Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway (2, 3, 4)
Name Description clathrin Adaptor Protein complex Medium chain
GO Annotations All APM3 GO evidence and references
    View Computational GO annotations for APM3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All APM3 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions APM3 All interactions details and references
74 total interaction(s) for 41 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-Western: 1
  • PCA: 1
  • Two-hybrid: 1
Genetic Interactions
  • Phenotypic Enhancement: 38
  • Phenotypic Suppression: 10
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 7
  • Synthetic Rescue: 2
Sequence Information
ChrII:779459 to 778008 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1452 779459..778008 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000492

APM3 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for APM3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for APM3]

1) Panek HR, et al.  (1997) Suppressors of YCK-encoded yeast casein kinase 1 deficiency define the four subunits of a novel clathrin AP-like complex. EMBO J 16(14):4194-204
2) Cowles CR, et al.  (1997) The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell 91(1):109-18
3) Yeung BG, et al.  (1999) Adaptor complex-independent clathrin function in yeast. Mol Biol Cell 10(11):3643-59
4) Odorizzi G, et al.  (1998) The AP-3 complex: a coat of many colours. Trends Cell Biol 8(7):282-8