REI1/YBR267W Summary Help

Standard Name REI1 1
Systematic Name YBR267W
Feature Type ORF, Verified
Description Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network (1, 2)
Name Description REquired for Isotropic bud growth 1
Chromosomal Location
ChrII:739841 to 741022 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All REI1 GO evidence and references
  View Computational GO annotations for REI1
Molecular Function
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
310 total interaction(s) for 215 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 24
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 27
  • Biochemical Activity: 1
  • Co-crystal Structure: 2
  • Co-fractionation: 2
  • PCA: 6
  • Reconstituted Complex: 2
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 143
  • Phenotypic Enhancement: 8
  • Phenotypic Suppression: 11
  • Positive Genetic: 66
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 4
  • Synthetic Rescue: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 393
Molecular Weight (Da) 45,862
Isoelectric Point (pI) 6.01
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:739841 to 741022 | ORF Map | GBrowse
This feature contains embedded feature(s): SLM6
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1182 739841..741022 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000471
References cited on this page View Complete Literature Guide for REI1
1) Iwase M and Toh-E A  (2004) Ybr267w is a new cytoplasmic protein belonging to the mitotic signaling network of Saccharomyces cerevisiae. Cell Struct Funct 29(1):1-15
2) Lebreton A, et al.  (2006) A functional network involved in the recycling of nucleocytoplasmic pre-60S factors. J Cell Biol 173(3):349-60
3) Badis G, et al.  (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32(6):878-87