AIM5/YBR262C Summary Help

Standard Name AIM5 1
Systematic Name YBR262C
Alias FMP51 2 , MCS12 3
Feature Type ORF, Verified
Description Mitochondrial inner membrane protein; subunit of the mitochondrial inner membrane organizing system (MitOS, MICOS, or MINOS), a scaffold-like structure on the intermembrane space side of the inner membrane which has a role in the maintenance of crista junctions and inner membrane architecture (3, 4, 5)
Name Description Altered Inheritance rate of Mitochondria 1
Chromosomal Location
ChrII:736040 to 735720 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All AIM5 GO evidence and references
  View Computational GO annotations for AIM5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Classical genetics
null
Large-scale survey
null
Resources
58 total interaction(s) for 31 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 19
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 17
  • Co-purification: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 13
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:736040 to 735720 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..321 736040..735720 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000466
References cited on this page View Complete Literature Guide for AIM5
1) Hess DC, et al.  (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407
2) Rehling, P., et al.  (2004) personal communication
3) Harner M, et al.  (2011) The mitochondrial contact site complex, a determinant of mitochondrial architecture.LID - 10.1038/emboj.2011.379 [doi] EMBO J ()
4) von der Malsburg K, et al.  (2011) Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. Dev Cell 21(4):694-707
5) Hoppins S, et al.  (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol 195(2):323-40