POP4/YBR257W Summary Help

POP4 BASIC INFORMATION

Standard Name POP4
Systematic Name YBR257W
Feature Type ORF, Verified
Description Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P (1, 2, 3, 4)
Name Description Processing Of Precursor RNAs
GO Annotations All POP4 GO evidence and references
    View Computational GO annotations for POP4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All POP4 Phenotype details and references
Large-scale survey
conditional
null
Interactions POP4 All interactions details and references
54 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 24
  • Affinity Capture-Western: 13
  • Two-hybrid: 13

Genetic Interactions
  • Dosage Rescue: 2
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Sequence Information
ChrII:728880 to 729719 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..840 728880..729719 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000461

POP4 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for POP4]

1) Chu S, et al.  (1997) A novel protein shared by RNase MRP and RNase P. RNA 3(4):382-91
2) Chamberlain JR, et al.  (1998) Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes Dev 12(11):1678-90
3)   personal communication
4) Houser-Scott F, et al.  (2002) Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P. Proc Natl Acad Sci U S A 99(5):2684-9