TRS20/YBR254C Summary Help

Standard Name TRS20 1
Systematic Name YBR254C
Feature Type ORF, Verified
Description One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder (1, 2, 3)
Name Description TRapp Subunit 1
Chromosomal Location
ChrII:724263 to 723736 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TRS20 GO evidence and references
  View Computational GO annotations for TRS20
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
conditional
Large-scale survey
conditional
null
reduction of function
repressible
Resources
214 total interaction(s) for 87 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 39
  • Affinity Capture-Western: 19
  • Co-fractionation: 2
  • Co-purification: 1
  • Two-hybrid: 13

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 113
  • Positive Genetic: 16
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 6

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:724263 to 723736 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..528 724263..723736 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000458
References cited on this page View Complete Literature Guide for TRS20
1) Sacher M, et al.  (2000) Identification and characterization of five new subunits of TRAPP. Eur J Cell Biol 79(2):71-80
2) Sacher M, et al.  (2001) TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell 7(2):433-42
3) Tiller GE, et al.  (2001) A recurrent RNA-splicing mutation in the SEDL gene causes X-linked spondyloepiphyseal dysplasia tarda. Am J Hum Genet 68(6):1398-407