ARC40/YBR234C Summary Help

Standard Name ARC40 1
Systematic Name YBR234C
Feature Type ORF, Verified
Description Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches (1, 2)
Name Description ARp2/3 Complex subunit 1
Chromosomal Location
ChrII:686592 to 685438 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ARC40 GO evidence and references
  View Computational GO annotations for ARC40
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
conditional
null
reduction of function
repressible
unspecified
Resources
185 total interaction(s) for 78 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 54
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 12
  • Co-purification: 2
  • PCA: 25
  • Reconstituted Complex: 3
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 15
  • Synthetic Lethality: 66

Resources
Expression Summary
histogram
Resources
Length (a.a.) 384
Molecular Weight (Da) 42,475
Isoelectric Point (pI) 7.03
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:686592 to 685438 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1155 686592..685438 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000438
References cited on this page View Complete Literature Guide for ARC40
1) Winter DC, et al.  (1999) Genetic dissection of the budding yeast Arp2/3 complex: a comparison of the in vivo and structural roles of individual subunits. Proc Natl Acad Sci U S A 96(13):7288-93
2) Pan F, et al.  (2004) ARPC1/Arc40 mediates the interaction of the actin-related protein 2 and 3 complex with Wiskott-Aldrich syndrome protein family activators. J Biol Chem 279(52):54629-36