KTR4/YBR199W Summary Help

Standard Name KTR4 1
Systematic Name YBR199W
Feature Type ORF, Verified
Description Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family of type II membrane proteins with a short cytoplasmic N-terminus, a membrane-spanning region and a highly conserved catalytic lumenal domain (2, 3)
Name Description Kre Two Related 3
Chromosomal Location
ChrII:618909 to 620303 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All KTR4 GO evidence and references
  View Computational GO annotations for KTR4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Large-scale survey
null
overexpression
Resources
23 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3
  • Co-purification: 2
  • PCA: 2

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 8
  • Positive Genetic: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 464
Molecular Weight (Da) 54,556
Isoelectric Point (pI) 4.56
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:618909 to 620303 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1395 618909..620303 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000403
References cited on this page View Complete Literature Guide for KTR4
1) Mallet L, et al.  (1994) Nucleotide sequence analysis of an 11.7 kb fragment of yeast chromosome II including BEM1, a new gene of the WD-40 repeat family and a new member of the KRE2/MNT1 family. Yeast 10(6):819-31
2) Lussier M, et al.  (1996) Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. J Biol Chem 271(18):11001-8
3) Lussier M, et al.  (1997) Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine-membered KRE2/MNT1 mannosyltransferase gene family in this organism. Yeast 13(3):267-74