Standard Name	SMP1 1
Systematic Name	YBR182C
Feature Type	ORF, Verified
Description	Putative transcription factor of the MADS-box family; involved in regulating the response to osmotic stress; SMP1 has a paralog, RLM1, that arose from the whole genome duplication (1, 2, 3)
Name Description	Second MEF2-like Protein 1 1

Chromosomal Location	ChrII:594864 to 593506 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SMP1
Molecular Function
Manually curated	DNA binding, bending (IDA) sequence-specific DNA binding (IDA) sequence-specific DNA binding transcription factor activity (IC)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress (IGI, IMP)
Cellular Component
Manually curated	cytoplasm (IDA) nucleus (IDA)

Binding motifs	Predicted SMP1 Binding Site Locations
	ACTACTAWWWWTAG 1 [Search intergenic regions for ACTACTAWWWWTAG] TAATTA 4 [Search intergenic regions for TAATTA]
Resources	ScerTF | UniProbe | YEASTRACT | YeTFaSCo

Classical genetics
null	hyperosmotic stress resistance: decreased resistance to Calcofluor White: decreased viability: decreased viable
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to cycloheximide: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	31 total interaction(s) for 28 unique genes/features.
Physical Interactions	Affinity Capture-Western: 2 Biochemical Activity: 1 Two-hybrid: 9
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 11 Phenotypic Enhancement: 1 Positive Genetic: 4 Synthetic Growth Defect: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:594864 to 593506 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1359 594864..593506 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000386