Standard Name	EHT1
Systematic Name	YBR177C
Feature Type	ORF, Verified
Description	Acyl-coenzymeA:ethanol O-acyltransferase; plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane; EHT1 has a paralog, EEB1, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description	Ethanol Hexanoyl Transferase 6

Chromosomal Location	ChrII:586162 to 584807 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for EHT1
Molecular Function
Manually curated	alcohol O-butanoyltransferase activity (IDA) serine hydrolase activity (IDA, ISM) short-chain carboxylesterase activity (IDA)
Biological Process
Manually curated	cellular lipid metabolic process (IMP) medium-chain fatty acid biosynthetic process (IDA, IMP) medium-chain fatty acid catabolic process (IMP)
Cellular Component
Manually curated	lipid particle (IDA)
High-throughput	mitochondrial outer membrane (IDA) mitochondrion (IDA)

Classical genetics
null	fatty acid accumulation: decreased viable
Large-scale survey
null	competitive fitness: increased resistance to streptomycin: decreased resistance to pentachlorophenol: decreased resistance to cycloheximide: decreased resistance to benzo[a]pyrene: decreased starvation resistance: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	66 total interaction(s) for 60 unique genes/features.
Physical Interactions	Affinity Capture-MS: 8 Biochemical Activity: 1 Co-fractionation: 1 Co-purification: 2 PCA: 17 Protein-peptide: 1 Reconstituted Complex: 4 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 25 Positive Genetic: 5 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:586162 to 584807 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1356 586162..584807 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000381