ECM31/YBR176W Summary Help

Standard Name ECM31 1
Systematic Name YBR176W
Feature Type ORF, Verified
Description Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate (1, 2, 3)
Name Description ExtraCellular Mutant 1
Chromosomal Location
ChrII:583720 to 584658 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ECM31 GO evidence and references
  View Computational GO annotations for ECM31
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Pathways
Classical genetics
null
unspecified
Large-scale survey
null
unspecified
Resources
20 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 6

Genetic Interactions
  • Negative Genetic: 8
  • Positive Genetic: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 312
Molecular Weight (Da) 34,465
Isoelectric Point (pI) 8.12
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:583720 to 584658 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..939 583720..584658 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000380
References cited on this page View Complete Literature Guide for ECM31
1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Entian KD, et al.  (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702
3) White WH, et al.  (2001) Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine. J Biol Chem 276(14):10794-800