SHE3/YBR130C Summary Help

SHE3 BASIC INFORMATION

Standard Name SHE3 1
Systematic Name YBR130C
Feature Type ORF, Verified
Description Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance (2, 3, 4, 5, 6)
Name Description Swi5p-dependent HO Expression 1
GO Annotations All SHE3 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All SHE3 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SHE3 All interactions details and references
79 total interaction(s) for 38 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 26
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 12
  • Biochemical Activity: 12
  • Co-fractionation: 1
  • Co-purification: 1
  • PCA: 4
  • Protein-RNA: 1
  • Reconstituted Complex: 3
  • Two-hybrid: 9
Genetic Interactions
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 6
Sequence Information
ChrII:496863 to 495586 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1278 496863..495586 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000334

SHE3 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SHE3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SHE3]

1) Jansen RP, et al.  (1996) Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins. Cell 84(5):687-97
2) Takizawa PA and Vale RD  (2000) The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. Proc Natl Acad Sci U S A 97(10):5273-8
3) Long RM, et al.  (2000) She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA. EMBO J 19(23):6592-601
4) Bohl F, et al.  (2000) She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p. EMBO J 19(20):5514-24
5) Shepard KA, et al.  (2003) Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis. Proc Natl Acad Sci U S A 100(20):11429-34
6) Estrada P, et al.  (2003) Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae. J Cell Biol 163(6):1255-66