Standard Name	MUD1 1
Systematic Name	YBR119W
Feature Type	ORF, Verified
Description	U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing (1, 2)
Name Description	Mutant U1 Die 1
Gene Product Alias	U1-A 2 , U1A 1

Chromosomal Location	ChrII:479338 to 480323 | ORF Map | GBrowse

	View Computational GO annotations for MUD1
Molecular Function
Manually curated	RNA binding (IGI, ISS) U1 snRNA binding (IPI)
Biological Process
Manually curated	mRNA splicing, via spliceosome (IGI)
Cellular Component
Manually curated	U1 snRNP (IDA) U2-type prespliceosome (IDA)

Classical genetics
null	metal resistance: decreased
Large-scale survey
null	cell cycle progression in G1 phase: decreased duration glycogen accumulation: decreased inositol excretion: increased competitive fitness: decreased haploproficient resistance to fluconazole: increased resistance to camptothecin: increased resistance to bleomycin: increased resistance to nickel(2+): increased resistance to mycophenolic acid: increased resistance to tunicamycin: increased resistance to neothyonidioside: decreased resistance to methyl methanesulfonate: decreased resistance to caffeine: increased vegetative growth: decreased rate vegetative growth: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	235 total interaction(s) for 122 unique genes/features.
Physical Interactions	Affinity Capture-MS: 143 Affinity Capture-RNA: 1 Affinity Capture-Western: 6 Co-localization: 1 Co-purification: 1 Two-hybrid: 5
Genetic Interactions	Negative Genetic: 60 Phenotypic Enhancement: 1 Positive Genetic: 10 Synthetic Growth Defect: 4 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:479338 to 480323 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..8 479338..479345 2011-02-03 1997-01-28 Intron 9..97 479346..479434 2011-02-03 1997-01-28 CDS 98..986 479435..480323 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (9 - 97)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000323