YSA1/YBR111C Summary Help

Standard Name YSA1
Systematic Name YBR111C
Alias RMA2 1
Feature Type ORF, Verified
Description Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate (2, 3, 4)
Chromosomal Location
ChrII:461873 to 461178 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YSA1 GO evidence and references
  View Computational GO annotations for YSA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
59 total interaction(s) for 56 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 3
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 46
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 231
Molecular Weight (Da) 26,087
Isoelectric Point (pI) 6.31
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:461873 to 461178 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..696 461873..461178 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000315
References cited on this page View Complete Literature Guide for YSA1
1) Entian KD, et al.  (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702
2) Dunn CA, et al.  (1999) Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance. J Biol Chem 274(45):32318-24
3) Rafty LA, et al.  (2002) Analysis of O-acetyl-ADP-ribose as a target for Nudix ADP-ribose hydrolases. J Biol Chem 277(49):47114-22
4) Song MG, et al.  (2013) Multiple Nudix family proteins possess mRNA decapping activity. RNA 19(3):390-9