IML3/YBR107C Summary Help

IML3 BASIC INFORMATION

Standard Name IML3
Systematic Name YBR107C
Alias MCM19
Feature Type ORF, Verified
Description Protein with a role in kinetochore function, localizes to the outer kinetochore in a Ctf19p-dependent manner, interacts with Chl4p and Ctf19p (1, 2)
Name Description Increased Minichromosome Loss 3
GO Annotations All IML3 GO evidence and references
    View Computational GO annotations for IML3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All IML3 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions IML3 All interactions details and references
107 total interaction(s) for 60 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 21
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 5
  • Biochemical Activity: 2
  • Co-localization: 3
  • Two-hybrid: 15
Genetic Interactions
  • Phenotypic Enhancement: 15
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 20
  • Synthetic Lethality: 20
  • Synthetic Rescue: 1
Sequence Information
ChrII:454524 to 453787 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..738 454524..453787 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000311

IML3 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for IML3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for IML3]

1) Ghosh SK, et al.  (2001) The IML3/MCM19 gene of Saccharomyces cerevisiae is required for a kinetochore-related process during chromosome segregation. Mol Genet Genomics 265(2):249-57
2) Pot I, et al.  (2003) Chl4p and iml3p are two new members of the budding yeast outer kinetochore. Mol Biol Cell 14(2):460-76
3) Entian KD, et al.  (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702