Standard Name	PHO88
Systematic Name	YBR106W
Feature Type	ORF, Verified
Description	Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations (1)
Name Description	PHOsphate metabolism

Chromosomal Location	ChrII:452658 to 453224 | ORF Map | GBrowse

	View Computational GO annotations for PHO88
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	phosphate ion transport (IGI, IMP, ISS)
Cellular Component
Manually curated	membrane (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	tRNA accumulation: increased metal resistance: decreased Gag accumulation: decreased CPY modification: decreased resistance to quinine: decreased
overexpression	acid phosphatase activity: increased
Large-scale survey
null	auxotrophy competitive fitness: decreased dessication resistance: decreased endocytosis: decreased fermentative growth: decreased rate haploinsufficient heat sensitivity: increased inviable metal resistance: decreased protein transport: abnormal resistance to hydroxyurea: increased resistance to cycloheximide: increased resistance to fenpropimorph: increased resistance to mycophenolic acid: increased resistance to oleate: decreased resistance to miconazole: decreased resistance to hydroxyurea: decreased resistance to benomyl: decreased resistance to fluconazole: decreased resistance to wortmannin: decreased resistance to quinine: decreased resistance to 4-chlorophenol: decreased resistance to 2,4-dichlorophenol: decreased resistance to bleomycin: decreased resistance to caffeine: decreased resistance to dimethyl sulfoxide: decreased resistance to lovastatin: decreased resistance to tunicamycin: increased resistance to L-1,4-dithiothreitol: decreased resistance to hygromycin B: decreased resistance to acrolein: decreased sporulation: decreased starvation resistance: decreased stress resistance: increased telomere length: decreased transposable element transposition: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	190 total interaction(s) for 163 unique genes/features.
Physical Interactions	Affinity Capture-MS: 10 Affinity Capture-RNA: 3 PCA: 140
Genetic Interactions	Negative Genetic: 16 Phenotypic Enhancement: 1 Phenotypic Suppression: 3 Positive Genetic: 6 Synthetic Growth Defect: 5 Synthetic Lethality: 4 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:452658 to 453224 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..567 452658..453224 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000310