Standard Name	PBY1 1
Systematic Name	YBR094W
Feature Type	ORF, Verified
Description	Putative tubulin tyrosine ligase associated with P-bodies; forms cytoplasmic foci upon DNA replication stress (1, 2)
Name Description	P-BodY associated protein 1

Chromosomal Location	ChrII:432036 to 434297 | ORF Map | GBrowse

	View Computational GO annotations for PBY1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND) NOT nuclear-transcribed mRNA catabolic process (IMP)
Cellular Component
Manually curated	cytoplasmic mRNA processing body (IDA)
High-throughput	cytoplasm (IDA)

Classical genetics
null	resistance to hydroxyurea: decreased resistance to selenium(2+): decreased
Large-scale survey
null	competitive fitness: decreased haploproficient resistance to hydroxyurea: decreased resistance to camptothecin: decreased resistance to methyl methanesulfonate: decreased resistance to tirapazamine: decreased resistance to tunicamycin: increased resistance to fenpropimorph: increased resistance to caffeine: increased resistance to bleomycin: increased starvation resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	100 total interaction(s) for 63 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9 Biochemical Activity: 1 PCA: 1 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 46 Phenotypic Enhancement: 3 Positive Genetic: 3 Synthetic Growth Defect: 19 Synthetic Lethality: 15
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:432036 to 434297 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2262 432036..434297 2011-02-03 2011-02-03
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000298