TEC1/YBR083W Summary

TEC1 BASIC INFORMATION

Standard Name	TEC1
Systematic Name	YBR083W
Alias	ROC1
Feature Type	ORF, Verified
Description	Transcription factor required for full Ty1 expression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member (1, 2)
Name Description	Transposon Enhancement Control 1

GO Annotations	All TEC1 GO evidence and references
	View Computational GO annotations for TEC1
Molecular Function
Manually curated	specific RNA polymerase II transcription factor activity (IDA)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	invasive growth in response to glucose limitation (IMP) positive regulation of transcription from RNA polymerase II promoter (IDA) pseudohyphal growth (IDA, IMP)
Cellular Component
Manually curated	nucleus (IDA)

Regulatory Role
Binding motifs	TEC1 Transcription Factor Binding Sites and References
	CATTCC CATTCYY
Regulatory modules	predicted: cellcycle ( 245 )

Mutant Phenotype	All TEC1 Phenotype details and references
Classical genetics
null	Ty1 RNA accumulation: decreased pseudohyphal growth: decreased subcellular morphology: abnormal transposable element transposition: decreased
overexpression	nuclear morphology: abnormal
unspecified	invasive growth: increased pseudohyphal growth: decreased
Large-scale survey
null	filamentous growth: decreased invasive growth: absent viable
overexpression	cell cycle progression: abnormal filamentous growth: increased

Interactions	TEC1 All interactions details and references
	56 total interaction(s) for 33 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 11 Biochemical Activity: 2 Protein-RNA: 1 Reconstituted Complex: 7
Genetic Interactions	Dosage Rescue: 6 Phenotypic Enhancement: 7 Phenotypic Suppression: 13 Synthetic Rescue: 3

Sequence Information

ChrII:409163 to 410623 | |

Last Update

Coordinates: 2004-07-16 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1461	409163..410623	2004-07-16	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000287

TEC1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for TEC1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TEC1]

1)	Laloux I, et al. (1990) TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene expression in Saccharomyces cerevisiae: cloning and molecular analysis. Mol Cell Biol 10(7):3541-50
2)	Kohler T, et al. (2002) Dual role of the Saccharomyces cerevisiae TEA/ATTS family transcription factor Tec1p in regulation of gene expression and cellular development. Eukaryot Cell 1(5):673-86

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