ECM2/YBR065C Summary Help

ECM2 BASIC INFORMATION

Standard Name ECM2 1
Systematic Name YBR065C
Alias SLT11 2
Feature Type ORF, Verified
Description Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p (2, 3, 4)
Name Description ExtraCellular Mutant 1
GO Annotations All ECM2 GO evidence and references
    View Computational GO annotations for ECM2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All ECM2 Phenotype details and references
Large-scale survey
null
Interactions ECM2 All interactions details and references
66 total interaction(s) for 42 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 40
  • Affinity Capture-Western: 1
  • Co-purification: 1
Genetic Interactions
  • Phenotypic Enhancement: 11
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 6
Sequence Information
ChrII:369676 to 368582 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1095 369676..368582 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000269

ECM2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for ECM2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ECM2]

1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Xu D, et al.  (1998) Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing. Mol Cell Biol 18(4):2055-66
3) Ben-Yehuda S, et al.  (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17
4) Xu D and Friesen JD  (2001) Splicing factor slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosome. Mol Cell Biol 21(4):1011-23