TCM62/YBR044C Summary

TCM62 BASIC INFORMATION

Standard Name	TCM62 1
Systematic Name	YBR044C
Feature Type	ORF, Verified
Description	Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone (1)
Name Description	TriCarboxylic acid cycle Mutant 1

GO Annotations	All TCM62 GO evidence and references
	View Computational GO annotations for TCM62
Molecular Function
Manually curated	unfolded protein binding (IMP)
Biological Process
Manually curated	mitochondrial respiratory chain complex II assembly (IMP, IPI)
Cellular Component
Manually curated	mitochondrial inner membrane (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All TCM62 Phenotype details and references
Classical genetics
null	acetic acid excretion: increased
Large-scale survey
null	resistance to amiodarone: decreased resistance to doxorubicin: decreased respiratory growth: decreased rate sporulation: abnormal transposable element transposition: decreased utilization of carbon source: decreased viable

Interactions	TCM62 All interactions details and references
	13 total interaction(s) for 13 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Reconstituted Complex: 3 Two-hybrid: 4
Genetic Interactions	Synthetic Haploinsufficiency: 1

Sequence Information

ChrII:326058 to 324337 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-16 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1722	326058..324337	2004-07-16	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000248

TCM62 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for TCM62

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TCM62]

1)	Dibrov E, et al. (1998) The Saccharomyces cerevisiae TCM62 gene encodes a chaperone necessary for the assembly of the mitochondrial succinate dehydrogenase (complex II). J Biol Chem 273(48):32042-8

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.