SCO2/YBR024W Summary

SCO2 BASIC INFORMATION

Standard Name	SCO2
Systematic Name	YBR024W
Feature Type	ORF, Verified
Description	Protein anchored to the mitochondrial inner membrane, similar to Sco1p and may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p (1)
Name Description	Suppressor of Cytochrome Oxidase deficiency 2

GO Annotations	All SCO2 GO evidence and references
	View Computational GO annotations for SCO2
Molecular Function
Manually curated	thioredoxin peroxidase activity (ISS)
Biological Process
Manually curated	copper ion transport (ISS)
Cellular Component
Manually curated	mitochondrial envelope (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All SCO2 Phenotype details and references
Classical genetics
overexpression	cell cycle progression in G1 phase: abnormal
Large-scale survey
null	viable
overexpression	inviable

Interactions	SCO2 All interactions details and references
	8 total interaction(s) for 8 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-Western: 1 Biochemical Activity: 1 Reconstituted Complex: 2 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 1

Sequence Information

ChrII:289445 to 290350 | |

Last Update

Coordinates: 2004-07-16 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..906	289445..290350	2004-07-16	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000228

SCO2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for SCO2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SCO2]

1)	Lode A, et al. (2002) Molecular characterization of Saccharomyces cerevisiae Sco2p reveals a high degree of redundancy with Sco1p. Yeast 19(11):909-22
2)	Glerum DM, et al. (1996) SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae. J Biol Chem 271(34):20531-5

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