Standard Name	SCO2
Systematic Name	YBR024W
Feature Type	ORF, Verified
Description	Protein anchored to mitochondrial inner membrane; may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p; SCO2 has a paralog, SCO1, that arose from the whole genome duplication (1, 2)
Name Description	Suppressor of Cytochrome Oxidase deficiency 3

Chromosomal Location	ChrII:289445 to 290350 | ORF Map | GBrowse

	View Computational GO annotations for SCO2
Molecular Function
Manually curated	thioredoxin peroxidase activity (ISS)
Biological Process
Manually curated	copper ion transport (ISS)
Cellular Component
Manually curated	mitochondrial envelope (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
overexpression	cell cycle progression in G1 phase: abnormal
Large-scale survey
null	competitive fitness: increased resistance to benzo[a]pyrene: decreased resistance to cycloheximide: decreased viable
overexpression	inviable vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	41 total interaction(s) for 33 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-Western: 1 Biochemical Activity: 1 PCA: 1 Reconstituted Complex: 2
Genetic Interactions	Dosage Rescue: 2 Negative Genetic: 30 Positive Genetic: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:289445 to 290350 | ORF Map | GBrowse
Last Update	Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..906 289445..290350 2004-07-16 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000228